HBV genotypes and antiviral-resistant variants in HBV infected subjects in Northern Italy.
نویسندگان
چکیده
HBV genotypes were investigated in sera/plasma from 97 HBV positive subjects. Genotype D was revealed in 80.4% followed by E in 6.2%. Genotypes A, B, and C were also found, as well as for the first time a new combination of HBV D and G genotypes. In a cohort of subjects of this population, the relationship with lamivudine and/or famciclovir-resistant HBV mutants was also investigated. Among 12 untreated subjects, 25% carried HBV drug-resistant strains suggesting that drug-resistant variants naturally exist in untreated Italian HBV chronically infected subjects.
منابع مشابه
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ورودعنوان ژورنال:
- The new microbiologica
دوره 29 1 شماره
صفحات -
تاریخ انتشار 2006